With the rise in bowel cancer cases among those under 50, scientists continue to search for the possible causes behind this alarming trend, which cannot be explained by genetic factors alone.
Here are the top 5 factors suspected of being linked to the increased incidence, according to ScienceFocus:
1. Obesity and Metabolic Disorders
Obesity, especially at a young age, is a major risk factor, as it is associated with chronic inflammation and hormonal changes that may promote the growth of cancerous cells.
2. Harmful Gut Bacteria (Colibactin)
Recent research suggests that some bacteria that produce the toxin colibactin may damage the DNA of colon cells, increasing the risk of developing the disease later in life.
3. Early Antibiotic Use
Overuse of antibiotics in childhood can disrupt the balance of the gut microbiome, allowing harmful bacteria to thrive.
4. Ultra-Processed Foods
A diet rich in processed foods is linked to immune system disorders and increased inflammation, in addition to its negative impact on beneficial gut bacteria.
5. Micro-environmental factors
These include microplastics and other pollutants that may affect the intestinal wall and alter the microbiome balance, potentially contributing to disease development.
Despite these indicators, researchers emphasize that the picture is still incomplete, and a deeper understanding of these factors could pave the way for more effective prevention and treatment methods in the future.